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AAHA Guidelines

Puppy Vaccine Schedule

A complete vaccination timeline for puppies from 6 weeks through adulthood, based on American Animal Hospital Association (AAHA) guidelines.

Vaccination Timeline

AgeVaccines
6-8 weeks
DHPP #1

Start core vaccines; may also begin Bordetella if needed

10-12 weeks
DHPP #2Leptospirosis #1 (if indicated)Bordetella (if not given earlier)

Continue core series; assess lifestyle for non-core vaccines

14-16 weeks
DHPP #3RabiesLeptospirosis #2 (if indicated)Lyme #1 (if indicated)

Final puppy DHPP; Rabies legally required in most states by 16 weeks

16-18 weeks
Canine Influenza #1 (if indicated)Lyme #2 (if indicated)

Complete non-core vaccine series as needed

1 year
DHPP boosterRabies boosterLeptospirosis (annual)Non-core vaccines as needed

First adult boosters; establishes long-term immunity

Adult (every 1-3 years)
DHPP (every 3 years)Rabies (per state law)Non-core vaccines annually as needed

Frequency depends on vaccine type and state requirements

Core vaccines (recommended for all dogs)
Non-core vaccines (based on lifestyle/risk)

Typical Vaccine Costs

DHPP/DAPP Combination
$25-50 per dose
Rabies
$15-35
Bordetella
$20-45
Leptospirosis
$15-35
Lyme Disease
$30-50
Canine Influenza
$40-60

* Prices are estimates and vary by location and provider. Low-cost clinics often offer lower prices.

Core Vaccines for Dogs

Core vaccines are recommended for all dogs regardless of lifestyle or location. For a quick overview of core vs non-core vaccines for both dogs and cats, see our vaccine hub.

Rabies

Core

Required by law in most states. Protects against the fatal rabies virus.

Schedule:

First dose at 12-16 weeks, then booster at 1 year, then every 1-3 years

Typical Cost:

$15-35

DHPP/DAPP Combination

Core

Combination vaccine protecting against distemper, hepatitis/adenovirus, parainfluenza, and parvovirus.

Schedule:

Starting at 6-8 weeks, every 3-4 weeks until 16 weeks, booster at 1 year, then every 3 years

Typical Cost:

$25-50

Non-Core Vaccines for Dogs

Non-core vaccines are recommended based on your dog's lifestyle and risk factors. Discuss with your veterinarian which ones are appropriate.

Bordetella (Kennel Cough)

Non-Core

Protects against bacterial cause of kennel cough. Often required for boarding, grooming, daycare.

Schedule:

As early as 8 weeks, then annually or every 6 months for high-risk dogs

Typical Cost:

$20-45

Leptospirosis

Non-Core

Bacterial disease spread through contaminated water/soil. Consider for dogs with outdoor exposure.

Schedule:

Starting at 12 weeks, booster 2-4 weeks later, then annually

Typical Cost:

$15-35

Lyme Disease

Non-Core

Tick-borne bacterial disease. Recommended in areas with high tick exposure.

Schedule:

Starting at 12 weeks, booster 2-4 weeks later, then annually

Typical Cost:

$30-50

Canine Influenza

Non-Core

Protects against dog flu strains. Often required for boarding, shows, and social dogs.

Schedule:

Starting at 6-8 weeks, booster 2-4 weeks later, then annually

Typical Cost:

$40-60

Rattlesnake Vaccine

Non-Core

May reduce severity of Western Diamondback rattlesnake bites. For dogs in rattlesnake areas.

Schedule:

Starting at 16 weeks, booster 1 month later, then annually (or more often in high-risk areas)

Typical Cost:

$25-50

Save on Puppy Vaccines

Puppy vaccine series can add up. Find low-cost clinics, retail locations, and vaccine events near you to save money.

Find Low-Cost Clinics

Important Disclaimer

Based on AAHA Guidelines: This schedule follows the American Animal Hospital Association canine vaccination guidelines. Your veterinarian may adjust based on your puppy's specific needs.

Not Medical Advice: Always consult with a licensed veterinarian for your puppy's vaccination plan.

Costs Are Estimates: Prices vary by location, provider type, and geographic area.